An efficient synthesis of chiral quaternary carbon centres with high optical purity via 1,3-chirality transfer
Abstract
An efficient synthesis of chiral quaternary carbon centres via Me2Cu(CN)Li2·BF3 or RCu(CN)Li·BF3(R ≠ Me) mediated 1,3-chirality transfer of α-alkyl-γ-mesyloxy-α,β-enoates is reported.