Issue 20, 1987

A simple, general distereoselective synthesis of 5-hydroxyalkylbutan-4-olides

Abstract

cis- and trans-Hex-4-enoic acids and their 6-n-propyl and n-butyl derivatives, when treated with a 1.1 molar excess of m-chloroperbenzoic acid and Amberlyst-15 as catalyst in CH2Cl2 at 20 °C, gave the corresponding threo- and erythro-5-hydroxyalkylbutan-4-olides in quantitative yields.

Article information

Article type
Paper

J. Chem. Soc., Chem. Commun., 1987, 1513-1514

A simple, general distereoselective synthesis of 5-hydroxyalkylbutan-4-olides

C. W. Jefford and Y. Wang, J. Chem. Soc., Chem. Commun., 1987, 1513 DOI: 10.1039/C39870001513

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