SCHEDULED MAINTENANCE
Oximes react with Michael acceptors and dipolarophiles, usually regio- and stereo-specifically, via a tandem Michael addition–1,3-dipolar cycloaddition process, to give isoxazolidines in good yield; analysis of the tandem process identifies four broad synthetic variants, and examples of those involving initial intermolecular Michael addition are given.
P. Armstrong, R. Grigg and W. J. Warnock, J. Chem. Soc., Chem. Commun., 1987, 1325 DOI: 10.1039/C39870001325
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