4,5-Dihydro-oxazole (1) has been anchored to silica gel, affording immobilized species that, in comparison with similar systems bound to polystyrene matrices, readily undergo hydrolytic cleavage of the oxazoline ring to give the supported amino alcohol and the free soluble carboxylic acid.
F. Minozzi and P. Venturello, J. Chem. Soc., Chem. Commun., 1987, 1255 DOI: 10.1039/C39870001255
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