Conversion of thiocarbonyl into carbonyl in uracil, uridine, and Escherichia coli transfer RNA using hypervalent iodine oxidation
Abstract
2-Thiouracil, 5-, and 6-methyl-2-thiouracil were converted into uracil, 5-, and 6-methyluracil by PhlO in acetone; the 4-thiouridine site in tRNA was transformed to uridine by Phl(OH)OSO2C6H4Me-p at pH 4.0.