Structures of two stereoisomers of a new type of indoloditerpene related to the tremorgenic mycotoxin paxilline, from Emericell desertorum and Emericella striata

Abstract

The structure elucidation of emindoles DA (1) and SA (2), indoloditerpenes from the mycelial extract of Emericella desortorum and Emericella striata, respectively, is reported, based on their ¹H and ¹³C n.m.r. spectra and an X-ray crystallographic study of emindole DA monoacetate (4); these are novel proto-type indoloditerpenes biologically related to paxilline (3).