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Issue 14, 1987
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Regioselective one pot approach to aminodeoxy sugars via aminosilanes

Abstract

A novel one-step synthesis of regioisomerically pure aminodeoxy sugars (6)–(11) has been achieved by trans-diaxial cleavage of the oxirane ring in 2,3-anhydro sugars (1)–(5) with N,N-diethyltrimethylsilylamine or its N,N-dimethyl analogue, using AlCl3 as catalyst; the reagents work under mild conditions and avoid the difficulties which sometimes are encountered in ring-opening reactions of epoxy sugars.

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Article type: Paper
DOI: 10.1039/C39870001073
J. Chem. Soc., Chem. Commun., 1987, 1073-1074

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    Regioselective one pot approach to aminodeoxy sugars via aminosilanes

    A. Malik, N. Kazmi, A. Q. Khan and Z. Ahmad, J. Chem. Soc., Chem. Commun., 1987, 1073
    DOI: 10.1039/C39870001073

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