Hetero-Diels–Alder reactions of ketones: a high-yielding synthesis of 2,2-disubstituted 2,3-dihydropyran-4-ones
Abstract
2,2-Disubstituted 2,3-dihydropyran-4-ones may be prepared in high yields by the Lewis acid-catalysed hetero-Diels–Alder reactions of electron-rich dienes with ketones bearing strongly electron-withdrawing substituents.