Issue 6, 1987

Preparation of optically active cyclic ether derivatives of amino acids and peptides

Abstract

Treatment of N-tritylmethioninol (1) or peptides (6), incorporating methionyl and amino alcohol residues, with Mel, followed by base mediated cyclisation of the thus derived sulphonium salts, provides the title compounds in excellent yields.

Article information

Article type
Paper

J. Chem. Soc., Chem. Commun., 1987, 474-475

Preparation of optically active cyclic ether derivatives of amino acids and peptides

K. Barlos, D. Papaioannou, S. Patrianakou, C. Sanida and T. Tsegenidis, J. Chem. Soc., Chem. Commun., 1987, 474 DOI: 10.1039/C39870000474

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