Issue 5, 1987

Synthesis of C-2″β- and C-2″α-fluoro avermectin B1a

Abstract

A synthesis of protected C-2β- and C-2α-fluoro oleandrosyl fluorides is presented; coupling of these carbohydrates with avermectin B1a monosaccharide 5-O-t-butyldimethylsilyl derivative, followed by deprotection, furnished the title compounds whose biological activity was evaluated.

Article information

Article type
Paper

J. Chem. Soc., Chem. Commun., 1987, 368-370

Synthesis of C-2″β- and C-2″α-fluoro avermectin B1a

C. Bliard, F. C. Escribano, G. Lukacs, A. Olesker and P. Sarda, J. Chem. Soc., Chem. Commun., 1987, 368 DOI: 10.1039/C39870000368

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