An efficient and stereoselective synthesisi of homoallylic alcohols via nickel-catalysed coupling of 5-alkyl-2,3-dihydrofurans with Grignard reagents
Abstract
The low-valent nickel-catalysed coupling of Grignard reagents with 5-alkyl-2,3-dihydrofurans is an efficient and stereoselective method for synthesising homoallylic alcohols provided appropriate care is taken in the workup.