Analytical information from doublet peaks in flow injection analysis. Part II. Determination of stability constants

Abstract

An equation was derived for the determination of a stability constant from a flow injection titration experiment in which the product of the reaction is monitored. This equation showed that if the product concentration at the equivalence points of the titration was used as the basis for the calculation, the method was independent of all the variables associated with the flow injection system, provided that a single-line manifold was used. If the system corresponded to that described by the well stirred mixing chamber model, then the time interval between the peaks could be used to determine the ratio of the stoicheiometric coefficients of the reactants. The use of the method is illustrated for the copper(II)-EDTA system giving values for log K in reasonable agreement with the literature values.