SCHEDULED MAINTENANCE
Charton's relation, that the pKa values of substituted guanidines are solely a function of σI, has been vindicated in a comprehensive study involving many more compounds. The resulting equation has been used, in conjunction with the pKa values of a range of guanidinoheterocycles, to derive the σI values for a number of heteroaryl substituents. Trends among the data are discussed; some apparent anomalies are noted and explained.
P. J. Taylor and A. R. Wait, J. Chem. Soc., Perkin Trans. 2, 1986, 1765 DOI: 10.1039/P29860001765
To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.
If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.
If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.
Read more about how to correctly acknowledge RSC content.
Please wait while we load your content...