Issue 5, 1986

A 1H and 13C nuclear magnetic resonance study of three quaternary salts of naloxone and oxymorphone

Abstract

The information from 1H–1H and 1H–13C correlation n.m.r. spectra allowed a complete assignment of the 1H and 13C spectra of three N,N-dialkylmorphinanium chloride derivatives (one N,N-diallyl and two N-allyl-N-methyl diastereoisomers). In the case of the steroisomers the configuration of the asymmetric N atom could be established on the basis of 1H chemical shift data and nuclear Overhauser effects.

Article information

Article type
Paper

J. Chem. Soc., Perkin Trans. 2, 1986, 735-738

A 1H and 13C nuclear magnetic resonance study of three quaternary salts of naloxone and oxymorphone

C. W. Funke, J. S. de Graaf, E. Buurman, H. Thalen and P. Vrijhof, J. Chem. Soc., Perkin Trans. 2, 1986, 735 DOI: 10.1039/P29860000735

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