Issue 0, 1986
From the journal:

Journal of the Chemical Society, Perkin Transactions 1

Dihydroimidazoles in synthesis: C-alkylation of 1-benzyl-2-(α-lithioalkyl)-4,5-dihydroimidazoles and a synthesis of alkanoic acids

Michael W. Anderson,   Raymond C. F. Jones  and  John Saunders  

Abstract

1-Benzyl-2-alkyl-4,5-dihydroimidazoles have been (laterally) metallated and C-alkylated by reaction with alkyl halides and an epoxide; intramolecular C-alkylation has led to a tetrahydro-5H-pyrrolo-[1,2-a]imidazole. Hydrolysis of the 4,5-dihydroimidazoles to produce alkanoic acids completes a homologation sequence.

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Article information

DOI
https://doi.org/10.1039/P19860000205
Article type
Paper

J. Chem. Soc., Perkin Trans. 1, 1986, 205-209

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Dihydroimidazoles in synthesis: C-alkylation of 1-benzyl-2-(α-lithioalkyl)-4,5-dihydroimidazoles and a synthesis of alkanoic acids

M. W. Anderson, R. C. F. Jones and J. Saunders, J. Chem. Soc., Perkin Trans. 1, 1986, 205 DOI: 10.1039/P19860000205

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