Issue 24, 1986

Self-indicating activated esters for use in solid phase peptide synthesis. Fluorenylmethoxycarbonylamino acid derivatives of 3-hydroxy-4-oxodihydrobenzotriazine

Abstract

The title esters are effective acylating agents in solid phase peptide synthesis; completion of acylation is indicated by fading of the transient yellow colour produced by ionisation of the liberated hydroxy component.

Article information

Article type
Paper

J. Chem. Soc., Chem. Commun., 1986, 1763-1765

Self-indicating activated esters for use in solid phase peptide synthesis. Fluorenylmethoxycarbonylamino acid derivatives of 3-hydroxy-4-oxodihydrobenzotriazine

E. Atherton, L. Cameron, M. Meldal and R. C. Sheppard, J. Chem. Soc., Chem. Commun., 1986, 1763 DOI: 10.1039/C39860001763

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