The reaction of (R)-(+)-isopropyl methylphosphinate (5) with bromobenene in the presence of Pd0 catalyst and triethylamine to afford (S)-(–)-isopropyl methylphenylphosphinate (6) proceeds with complete retention of configuration via a front-sided attack by phenylpalladium bromide on the phosphorus nucleophile.
Y. Xu and J. Zhang, J. Chem. Soc., Chem. Commun., 1986, 1606 DOI: 10.1039/C39860001606
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