New features of isoxazole chemistry. The reaction of ethyl 4-nitro-3-phenylisoxazole-5-carboxylate with 2,3-dimethylbuta-1,3-diene
Abstract
The title compound (2) was found to undergo a (2 + 4) cycloaddition with 2,3-dimethylbuta-1,3-diene affording the tetrahydro-1,2-benzisoxazole (3), which could be easily converted into the corresponding dihydro derivative (4) by elimination of the NO2 and CO2Et groups.