Issue 16, 1986

Synthesis of linear coumarins via para-Claisen rearrangement of coumarate ester derivatives: total synthesis of suberosin, demethylsuberosin, and ostruthin

Abstract

Heating 2′-O-prenylated derivatives of 4′-O-benzyl methyl coumarates (3) furnishes the corresponding linear prenylated umbelliferones (1) directly via sequential para-Claisen rearrangement and relactonisation.

Article information

Article type
Paper

J. Chem. Soc., Chem. Commun., 1986, 1264-1266

Synthesis of linear coumarins via para-Claisen rearrangement of coumarate ester derivatives: total synthesis of suberosin, demethylsuberosin, and ostruthin

N. Cairns, L. M. Harwood and D. P. Astles, J. Chem. Soc., Chem. Commun., 1986, 1264 DOI: 10.1039/C39860001264

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