A new ditopic host molecule (3), composed of the macromonocyclic 1,4,7,10,13,16-hexa-azacyclo-octadecane (1) and the macrocyclic polyether benzo-15-crown-5 (2) covalently linked, forms stable 1 : 1 complexes with zwitterionic molecules such as amino acids, peptides, and dopamine in aqueous solution at neutral pH.
E. Kimura, H. Fujioka and M. Kodama, J. Chem. Soc., Chem. Commun., 1986, 1158 DOI: 10.1039/C39860001158
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