The synthesis of renin inhibitors containing a novel amino-analogue of statine is described and inhibitory potencies are compared with those of statine congeners; the crystal structure of the aminostatine derivative (6) is reported.
R. J. Arrowsmith, K. Carter, J. G. Dann, D. E. Davies, C. J. Harris, J. A. Morton, P. Lister, J. A. Robinson and D. J. Williams, J. Chem. Soc., Chem. Commun., 1986, 755 DOI: 10.1039/C39860000755
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