Issue 4, 1986

The synthesis and absolute configuration of thiosphingomyelins

Abstract

Four diastereoisomers of a thiophosphoryl analogue of sphingomyelin were synthesized by a general method employing phosphoroamidites and the absolute configurations of (+)-erythro-thiosphingomyelins at phosphorus were determined by stereospecific hydrolysis in the presence of phospholipases C.

Article information

Article type
Paper

J. Chem. Soc., Chem. Commun., 1986, 329-331

The synthesis and absolute configuration of thiosphingomyelins

K. S. Bruzik, J. Chem. Soc., Chem. Commun., 1986, 329 DOI: 10.1039/C39860000329

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