Separation and determination of food colours in pharmaceutical preparations by column chromatography
Abstract
Food colours were extracted from pharmaceutical preparations on an Amberlite XAD-2 resin. From the food colours retained, selective elutions of disulphonic acid derivatised (DSD) and trisulphonic acid derivatised (TSD) food colours were carried out using two different strengths of methanolic sulphuric acid. A quantitative determination of these separated food colours was carried out spectrophotometrically.