1H and 13C nuclear magnetic resonance identification of the products of the reaction of NN-dialkylformamide dimethyl acetals with secondary amines

Abstract

Eight reactions of NN-dialkylformamide dimethyl acetals with secondary amines have been followed by means of ¹H n.m.r. The reaction products were not only other amide acetals but also ester aminals and orthoamides. Therefore secondary amines exchanged the amine moiety and the methoxy group of the amide acetal. The relative concentrations of products at equilibrium have been estimated. The ¹³C chemical shifts for substrates and some products have been reported.