The preparation and rearrangements of 5-acyl-2-phenyl-4-substituted 6H-1,3-thiazines. X-Ray molecular structure of 3-acetyl-2-ethoxycarbonyl-4-(3-oxobutylthio)-5-phenylpyrrole

Abstract

5-Acyl-2-phenyl-4-substituted 6H-1,3-thiazines are prepared by the reaction of N′,N′-substituted N²-thiobenzoylformamidines with methyl vinyl ketone or acrylaldehyde. Rearrangement catalysed by base and subsequent condensation with the acrylic reagent gives substituted pyrrolyl sulphides or substituted 2,6-dihydrothiopyrano[2,3-c]pyrrole.