A novel and efficient synthesis of fluoromethyl phenyl sulphone and its use as a fluoromethyl Wittig equivalent
Abstract
A new synthesis of fluoromethyl phenyl sulphone (2) and the reaction conjugate base (3) with carbonyl compounds provides β-fluoro-alcohols (5), which are utilized to prepare terminal vinyl fluorides (8)viaα-fluoro-α,β-unsaturated sulphones (6).