1,2,4-Trioxanes bearing a hydrogen substituent at the C-3 position when treated with trithylamine undergo scission of the oxygen-oxygen bond to give the corresponding 1,2-diol monoesters in high yields; similar treatment of a bridged 1,2,4-trioxane afforded the related γ-hydroxy-δ-lactone and its isomeric spirocyclic δ-lactone in 90% yield.
C. W. Jefford, S. Kohmoto, J. Rossier and J. Boukouvalas, J. Chem. Soc., Chem. Commun., 1985, 1783 DOI: 10.1039/C39850001783
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