Issue 23, 1985

Catalytic asymmetric induction from prochiral cyclic acid anhydrides using cinchona alkaloids

Abstract

Asymmetric ring-opening of prochiral cyclic acid anhydrides (1) with methanol was effected by a catalytic amount of cinchona alkaloids (2) with an enantiomeric excess of up to 70% and the product was converted into optically active lactones.

Article information

Article type
Paper

J. Chem. Soc., Chem. Commun., 1985, 1717-1719

Catalytic asymmetric induction from prochiral cyclic acid anhydrides using cinchona alkaloids

J. Hiratake, Y. Yamamoto and J. Oda, J. Chem. Soc., Chem. Commun., 1985, 1717 DOI: 10.1039/C39850001717

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