Issue 20, 1985

A synthesis of (+)-milbemycin β3. The 3,4-dihydro-2H-pyran approach

Abstract

Nucleophilic scission of oxirane (8) by vinyl alanate (4) and oxirane (11) by metallated 3,4-dihydro-2H-pyran (15) were key steps in the synthesis of (+)-milbemycin β3(1).

Article information

Article type
Paper

J. Chem. Soc., Chem. Commun., 1985, 1388-1389

A synthesis of (+)-milbemycin β3. The 3,4-dihydro-2H-pyran approach

C. Yeates, S. D. A. Street, P. Kocienski and S. F. Campbell, J. Chem. Soc., Chem. Commun., 1985, 1388 DOI: 10.1039/C39850001388

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