Issue 9, 1985

Reaction of silyl ketene acetals with N-trimethylsilyl imines: a route to N-unsubstituted azetidin-2-ones

Abstract

Reaction of N-trimethylsilyl imines with silyl ketene acetals in the presence of ZnI2 and t-butyl alcohol, followed by treatment in situ of the intermediate N-silyl β-aminoesters with MeMgBr, leads to N-unsubstituted azetidin-2-ones in good yield.

Article information

Article type
Paper

J. Chem. Soc., Chem. Commun., 1985, 539-540

Reaction of silyl ketene acetals with N-trimethylsilyl imines: a route to N-unsubstituted azetidin-2-ones

E. W. Colvin and D. G. McGarry, J. Chem. Soc., Chem. Commun., 1985, 539 DOI: 10.1039/C39850000539

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