The current belief that ring strain relief is the major driving force in the reactivity of small rings disproved by quantitative data obtained for the SN2 ring-opening reaction of cyclic ammonium ions.
M. L. Di Vona, G. Illuminati and C. Lillocci, J. Chem. Soc., Chem. Commun., 1985, 380 DOI: 10.1039/C39850000380
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