Conformational dependence of the β-deuterium equilibrium isotope effect in acyclic carbocations. Suppression of hyperconjugation by restricted rotation in the 2,4,4,6-tetramethylheptyl cation
Abstract
Steric inhibition of hyperconjunction leads to suppression of the equilibrium isotope effect which in turn is used to assign conformations of acyclic carbocations in solution.