High-performance liquid chromatographic determination of pyrrolizine isopropyl carbamate
Abstract
A rapid, sensitive and precise HPLC method for the determination of pyrrolizine isopropyl carbamate in an emulsion formulation is presented. Mean recoveries for amounts ranging from 100 to 1500 ng were between 98.1 and 102.1%. The coefficient of variation was less than 2%. The determination was achieved using the dimethoxy derivative as an internal standard.