Spectrophotometric methods for the determination of o-dihydroxybenzene derivatives

Abstract

Methods are described for the determination of o-dihydroxybenzene derivatives using p-aminoacetophenone (for catechol, guaiacol, eugenol and dopamine), thiosemicarbazide or isoniazid in the presence of sodium metaperiodate. The methods are reproducible and specific for these compounds. The method using p-aminoacetophenone-periodate is extended to the determination of eugenol in clove oil and dopamine in pharmaceutical preparations.