The reactions of 4,4-dialkylbuta-2,3-dienenitriles and 3-phenylpropynenitrile with guanidine and acetamide have been investigated; a number of 6-alkyl-2,4-diaminopyrimidines and 6-alkyl-2-methyl-4-aminopyrimidines as well as 2,4-diamino-6-phenylpyrimidine and 4-amino-2-methyl-6-phenyl-pyrimidine have been synthesised.
S. R. Landor, P. D. Landor and V. E. Williams, J. Chem. Soc., Perkin Trans. 1, 1984, 2677 DOI: 10.1039/P19840002677
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