Issue 21, 1984

Biosynthesis of the polyether antibiotic monensin-A. Incorporation of [2-2H2]-, (R)-[2-2H1]- and (S)-[2-2H1]-propionate

Abstract

The incorporation of [2-2H2]- and (S)-[2-2H1]-propionate into monensin-A in cultures of Streptomyces cinnamonensis occurs with retention of label only at C(4) and C(6) in the antibiotic, whereas during the incorporation of (R)-[2-2H1]propionate the deuterium label is lost to the medium.

Article information

Article type
Paper

J. Chem. Soc., Chem. Commun., 1984, 1421-1423

Biosynthesis of the polyether antibiotic monensin-A. Incorporation of [2-2H2]-, (R)-[2-2H1]- and (S)-[2-2H1]-propionate

G. R. Sood, J. A. Robinson and A. A. Ajaz, J. Chem. Soc., Chem. Commun., 1984, 1421 DOI: 10.1039/C39840001421

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