Issue 19, 1984

Reductive radical decarboxylation of amino-acids and peptides

Abstract

Radicals generated from N-protected α-amino-acids by photolysis of their N-hydroxypyridine-2-thione esters at room temperature are efficiently quenched by t-butyl thiol to give decarboxy-acids; comparable reactions have been carried out on the side chain carboxy groups of suitably protected aspartic and glutamic acids.

Article information

Article type
Paper

J. Chem. Soc., Chem. Commun., 1984, 1298-1299

Reductive radical decarboxylation of amino-acids and peptides

D. H. R. Barton, Y. Hervé, P. Potier and J. Thierry, J. Chem. Soc., Chem. Commun., 1984, 1298 DOI: 10.1039/C39840001298

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Spotlight

Advertisements