The regiospecific synthesis of the novel anthracycline 6-deoxycarminomycin (14b)is reported: the construction of the aglycone is based on the coupling of 1,4,5-trimethoxy-3-lithionaphthlene(3) to lactone(9) in a regioselective fashion, a new synthetic approach which provides a general route to 6-deoxyanthracyclinones.
F. Angelucci, F. Arcamone, G. Barchielli, A. Suarato, E. Vanotti and S. Penco, J. Chem. Soc., Chem. Commun., 1984, 530 DOI: 10.1039/C39840000530
To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.
If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.
If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.
Read more about how to correctly acknowledge RSC content.
Please wait while we load your content...