Studies of nickel absorption in rats using inductively coupled plasma atomic-emission spectrometry and liquid scintillation counting

Abstract

A comparison of the absorption by rats of orally dosed soluble ⁶³NiCl₂ and insoluble Raney nickel in polyethylene glycol 200 is reported. ⁶³Ni in whole blood was determined by liquid scintillation counting. The analytical technique used for the determination of Ni derived from the absorption of Raney Ni was inductively coupled plasma atomic-emission spectrometry to avoid the use of radiolabelled Raney Ni.