Micellar effects upon the acid hydrolysis of N-acylimidazoles

Abstract

The acid-catalysed hydrolysis of various N-acylimidazoles has been studied in the presence of anionic [sodium dodecyl sulphate (NaLS)] and cationic [cetyltrimethylammonium bromide (CTABr)] surfactants. For the hydrolysis of the N-lauroyl derivative, CTABr causes a rate decrease on increasing the pH in the range where the observed rate constants level off in water, whereas NaLS does not affect the slope of the rate profile in the same pH range.