trans-α-(Carboxycyclopropyl)glycine, a constituent of ackee seed (Blighia sapida), has been synthesized via the key intermediate ethyl (E)-4,4-diethoxybut-2-enoate
S. R. Landor, P. D. Landor and M. Kalli, J. Chem. Soc., Perkin Trans. 1, 1983, 2921 DOI: 10.1039/P19830002921
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