Studies of terpenoid biosynthesis. Part 29. The cleavage of the sterol side chain in the biosynthesis of demethoxyviridin
Abstract
The structures of a group of C6 and C7 alcohols obtained from Nodulisporium hinnuleum have been elucidated. When biosynthesized from [2-14C] mevalonic acid they have been shown to have a specific activity consistent with a common origin with their co-metabolite, demethoxyviridin. The number of [2-2H2] mevalonoid hydrogen atoms which were incorporated suggests that they were formed initially at the aldehyde oxidation level.