Method for the direct determination of enthalpies of transfer between immiscible solvents using an isoperibol flow microcalorimeter

Abstract

A method is presented which enables the enthalpies of transfer of organic solutes between immiscible solvents to be measured directly using flow microcalorimetry. The method is novel, and is based on the principles of solute distribution occurring between segmented flowing streams of phases within the flow-mix cell of an isoperibol flow microcalorimeter, followed by separation of the two phases immediately after the flow-mix cell using a phase-separating device.