A procedure for estimating the local effective charge on a protein surface from association constants for surface reactions of metalloproteins with inorganic complexes is outlined; results obtained are consistent with structural information.
S. K. Chapman, J. D. Sinclair-Day, A. G. Sykes, S. Tam and R. J. P. Williams, J. Chem. Soc., Chem. Commun., 1983, 1152 DOI: 10.1039/C39830001152
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