Cyclisation of alkynecarboxylic acids: a route to an oxaspirolactone
Abstract
Pent-4-yonic acid, in various alcohols, was cyclised in the presence of yellow mercury(II) oxide to 4,5-dihydro-5-alkoxy-5-methylfuran-2(3H)-ones; 8-hydroxyoct-4-yonic acid was also cyclised in dimethylformamide to 1,6-dioxaspiro[4.5]decan-2-one in good yield.