Issue 14, 1983

Asymmetric synthesis of mellein methyl ether: use of ortho-toluate carbanions generated by chiral bases

Abstract

An ortho-toluate carbanion generated from (2) by the chiral lithium amide base of (6), (7), or (11) undergoes an enantioselective aldol-type reaction with acetaldehyde to give mellein methyl ether (3), in up to 53% enantiometric excess.

Article information

Article type
Paper

J. Chem. Soc., Chem. Commun., 1983, 764-765

Asymmetric synthesis of mellein methyl ether: use of ortho-toluate carbanions generated by chiral bases

A. C. Regan and J. Staunton, J. Chem. Soc., Chem. Commun., 1983, 764 DOI: 10.1039/C39830000764

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Spotlight

Advertisements