A stereoselective synthesis of α-isosparteine
Abstract
Successive cycloaddition of Δ1-piperidiene 1-oxide to 4H-pyran proceeded regio- and stereo-selectively to afford a 2:1 adduct, catalytic hydrogenation of which gave α-isosparteine in high yield.
Successive cycloaddition of Δ1-piperidiene 1-oxide to 4H-pyran proceeded regio- and stereo-selectively to afford a 2:1 adduct, catalytic hydrogenation of which gave α-isosparteine in high yield.
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H. Oinuma, S. Dan and H. Kakisawa, J. Chem. Soc., Chem. Commun., 1983, 654 DOI: 10.1039/C39830000654
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