Issue 8, 1983

Synthesis of fused β-lactams by copper-promoted intramolecular aromatic substitution

Abstract

Competition between intramolecular aromatic substitution and elimination of the C-4 substituent occurs on heating the monocyclic azetidinones (3) in the presence of copper powder; steric hindrance favours the formation of the tricyclic azetidinones (4).

Article information

Article type
Paper

J. Chem. Soc., Chem. Commun., 1983, 431-432

Synthesis of fused β-lactams by copper-promoted intramolecular aromatic substitution

R. Joyeau, Y. Dugenet and M. Wakselman, J. Chem. Soc., Chem. Commun., 1983, 431 DOI: 10.1039/C39830000431

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