Voltammetric studies of zomepirac sodium and its determination in tablets by differential-pulse polarography

Abstract

A simple differential-pulse polarographic method has been developed for the determination of zomepirac sodium in tablets. Britton - Robinson buffer of pH 11.0, containing 5% V/V of methanol, was employed as the supporting electrolyte. The peak potential occurs at – 1.50 V. Results obtained by the proposed method are in excellent agreement with those provided by both the official and the manufacturer's methods of assay. It was found that commonly used tablet excipients did not interfere in the analyses.