Synthesis of bis(imides) and bis(half amides) of NN′-ethylenebis(iminodiacetic acid)

Abstract

NN′-Disubstituted derivativesof the bis-(imide) of NN′-ethylenebis(iminodiacetic acid) were prepared by alkylation of the di-sodium derivative of the bis(imide). The hydrolysis and methanolysis of the bis(imide) and some of its NN′-disubstituted derivatives were promoted by copper(II) and afforded copper complexes from which the expected bis(half amides) of NN′-ethylenebis(iminodiacetic acid) were obtained by the action of hydrogen sulphide.